Fumaric acid, tseem hu ua corydalic acid los yog lichenic acid, yog fumaric acid (IUPAC lub npe: (E)-butenic acid), tsis muaj kob, flammable crystal, carboxylic acid muab tau los ntawm butene. Nws cov tshuaj formula yog C4H4O4. Kev kub hnyiab fumaric acid tso tawm cov pa phem ntawm cov txiv neej anhydride fumes. Nws yog ib tus neeg koom nrog lub voj voog citric acid, muaj cov ntxhiab tsw qab, thiab tuaj yeem pom hauv * Corydalis *, * Boletus *, lichens, thiab Icelandic seaweed.
Fumaric acid yog siv rau hauv kev tsim cov polyester resins thiab polyols, nrog rau cov mordant nyob rau hauv dyes thiab ib tug flavoring neeg sawv cev. Nws yog ib qho khoom noj khoom haus ntxiv thiab kev noj haus ntxiv, thiab qee zaum siv los hloov cov tartaric acid hauv dej haus los yog ci hmoov.
Biology: Cells siv fumaric acid los tsim lub zog ntawm zaub mov. Tib neeg cov tawv nqaij kuj tsim fumaric acid thaum raug tshav ntuj.
Pharmacological Actions
Txij li thaum psoriasis qee zaum raug ntaus nqi los ntawm qhov tsis txaus ntawm kev tsim cov fumaric acid hauv daim tawv nqaij, fumaric acid qee zaum siv los kho tus mob no. Thawj koob tshuaj yog 60-105 mg txhua hnub, maj mam nce mus rau 1290 mg txhua hnub. Cov kev mob tshwm sim ntawm kev siv fumaric acid muaj xws li teeb meem rau lub raum los yog digestive, thiab daim tawv nqaij liab, feem ntau vim yog overdose. Kev siv ntev ntev tuaj yeem ua rau leukopenia.
Khoom noj khoom haus
Txij li xyoo 1946, fumaric acid tau siv los ua zaub mov acidifier vim nws tsis yog - toxicity. Nws yog dav siv nyob rau hauv dej haus thiab ci hmoov uas hais txog purity, xws li Viagra txiv hmab txiv ntoo kua txiv. Nws kuj yog siv los ua ib qho kev hloov rau tartaric acid, thiab qee zaum ua ib qho kev hloov rau citric acid. Txhawm rau kom muaj qhov zoo sib xws rau citric acid, qhov piv ntawm fumaric acid rau citric acid yog 0.91g rau 1.36g.